第18卷 第5期中国地方病学杂志Vol.18,No.5
1999年9月ChineseJournalofEndemiology1999-09
【临床观察】
硒维康治疗地方性砷中毒临床效果观察
侯少范1,杨林生1,李德珠1,王丽珍1,王五一1,陆毅伦1武克恭2,夏雅娟2,田素梅2,秦月娟2,李艳红2,于广军2
(1.中国科学院地理研究所,北京100101;2.内蒙古地方病防治研究所,内蒙古呼和浩特010020)
[摘要] 目的 观察有机硒制剂治疗地方性砷中毒临床效果。方法 切断高砷水源,改饮低砷水,并服用硒维康治疗,以体征改变为主,参考症状变化作为综合判定指标。结果 硒治疗组有效率88.00%,不变7.00%,恶化4.00%;对照组分别为31.39%,40.70%和15.12%。有机硒排砷作用非常显著。结论 有机硒制剂可作为有效的治疗砷中毒的药物。
[关键词] 砷中毒;有机硒;治疗;排砷作用
[中图分类号]R599.9 [文献标识码]A [文章编号]1000-4955(1999)05-0369-04ObservationofclinicaleffectoftreatmentofendemicarsenismwithXiweikangHOUShao-fan,YANGLin-sheng,LIDe-zhu,etal
(Instituteofgeography,ChineseAcademyofScience,Beijing100101,China)
[Abstract] Objective Toobservetheclinicaleffectoftreatmentofendemicarsenismwithorganicseleniumpreparation.Methods Toshutoffhighcontentofarsenicsourceofwaterandturntodrinklowcontentofarsenicwater,moreover,totreatpatientswithXiweikang,andthentomakesyntheticallyindexesmainlywithchangesofpatients'signsandwithsymptom'svariationofpatientsforreference.Results Therewere88.00%ofpatientstakingaturnforbetterinseleni-um-therapygroup.Correspondingly,therewere31.39%incontrolgroup;7.00%ofpatientsofse-lenium-therapygroupkeptoriginalstate,andsodid40.70%ofpatients'conditionincontrolgoup;Therewere4.00%ofpatientsdeterioratinginselenium-therapygroup,andsodid15.12%ofpatients'conditionincontrolgroup.Organicseleniumaffectedexcretionofarsenicobviously.Con-clusions Organicseleniumpreparationcanberegardedasaeffectivemedicinefortreatingendemicarsenism.
[Keywords] Arsenism;Organicselenium;Treatment;Excretionofarsenic
第18卷 第5期中国地方病学杂志Vol.18,No.5
1999年9月ChineseJournalofEndemiology1999-09
【临床观察】
硒维康治疗地方性砷中毒临床效果观察
侯少范1,杨林生1,李德珠1,王丽珍1,王五一1,陆毅伦1武克恭2,夏雅娟2,田素梅2,秦月娟2,李艳红2,于广军2
(1.中国科学院地理研究所,北京100101;2.内蒙古地方病防治研究所,内蒙古呼和浩特010020)
[摘要] 目的 观察有机硒制剂治疗地方性砷中毒临床效果。方法 切断高砷水源,改饮低砷水,并服用硒维康治疗,以体征改变为主,参考症状变化作为综合判定指标。结果 硒治疗组有效率88.00%,不变7.00%,恶化4.00%;对照组分别为31.39%,40.70%和15.12%。有机硒排砷作用非常显著。结论 有机硒制剂可作为有效的治疗砷中毒的药物。
[关键词] 砷中毒;有机硒;治疗;排砷作用
[中图分类号]R599.9 [文献标识码]A [文章编号]1000-4955(1999)05-0369-04ObservationofclinicaleffectoftreatmentofendemicarsenismwithXiweikangHOUShao-fan,YANGLin-sheng,LIDe-zhu,etal
(Instituteofgeography,ChineseAcademyofScience,Beijing100101,China)
[Abstract] Objective Toobservetheclinicaleffectoftreatmentofendemicarsenismwithorganicseleniumpreparation.Methods Toshutoffhighcontentofarsenicsourceofwaterandturntodrinklowcontentofarsenicwater,moreover,totreatpatientswithXiweikang,andthentomakesyntheticallyindexesmainlywithchangesofpatients'signsandwithsymptom'svariationofpatientsforreference.Results Therewere88.00%ofpatientstakingaturnforbetterinseleni-um-therapygroup.Correspondingly,therewere31.39%incontrolgroup;7.00%ofpatientsofse-lenium-therapygroupkeptoriginalstate,andsodid40.70%ofpatients'conditionincontrolgoup;Therewere4.00%ofpatientsdeterioratinginselenium-therapygroup,andsodid15.12%ofpatients'conditionincontrolgroup.Organicseleniumaffectedexcretionofarsenicobviously.Con-clusions Organicseleniumpreparationcanberegardedasaeffectivemedicinefortreatingendemicarsenism.
[Keywords] Arsenism;Organicselenium;Treatment;Excretionofarsenic